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    刘延友简介

    发布时间:2016/6/2 编辑:白霜 作者:system 点击:1131

      刘延友简介:

      1985年7月,医学学士,重庆医科大学;1990年7月,医学硕士,重庆医科大学;

      2005年7月,医学博士,四川大学。1985年至2002年,曾经涉及临床,教学,科研和行政等领域。2005年以来,在四川大学华西基础医学与法医学院主要从事科研与教学工作。

      研究领域包括生物医学工程,生理学与时间生物学。主要从事生物节律的产生机制,生物节律及其基因在生理和病理过程中的作用,如:代谢,肥胖,药物依赖等。主持和完成了包括“973”,国家自然科学基金等10余项国家、省部级科研课题。

      联系方式: Email: liuyanyou@126.com

      近几年来发表的主要文章:

      The circadian Clock gene regulates acrosin activity of sperm through serine protease inhibitor A3K.  Exp Biol Med (Maywood). 2016 Jan;241(2):205-15.

      The noncircadian function of the circadian Clock gene in the regulation of male fertility. J Biol Rhythms. 2013 Jun;28(3):208-17.

      Characteristics of infradian and circadian rhythms in the persistent vegetative state. J Int Med Res. 2011;39(6):2281-7.

      Characteristics of circadian rhythm in patients with intracerebral hemorrhage before death. Neurosciences (Riyadh). 2011 Oct; 16(4):340-6.

      Downregulation of Clock in circulatory system leads to an enhancement of fibrinolysis in mice. Exp Biol Med (Maywood). 2011 Sep; 236(9):1078-84.

      The association of CLOCK gene T3111C polymorphism and hPER3 gene 54-nucleotide repeat polymorphism with Chinese Han people schizophrenics. Mol Biol Rep. 2011 Jan; 38(1): 349-54.

      High expression of the circadian gene mPer2 diminishes the radiosensitivity of NIH 3T3 cells. Braz J Med Biol Res. 2009 Oct;42(10):882-91.

      Behavioral change related to Wenchuan devastating earthquake in mice. Bioelectromagnetics. 2009 Dec;30(8):613-20.

      Circadian blood pressure and heart rate characteristics in haemorrhagic vs ischaemic stroke in Chinese people. J Hum Hypertens. 2010 Mar;24(3):165-74.

      Circadian effects on outcome following surgery for intracerebral hemorrhage in humans? Brain Res. 2009 Mar 3;1258:78-85.

      High expression of circadian gene mPer2 diminishes radiosensitivity of tumor cells. Cancer Biother Radiopharm. 2008 Oct;23(5):561-70.

      Telomerase reconstitution contributes to resetting of circadian rhythm in fibroblasts. Mol Cell Biochem. 2008 Jun;313(1-2):11-8.

      Inhibition of tumorigenesis by intratumoral delivery of the circadian gene mPer2 in C57BL/6 mice. Cancer Gene Ther. 2007 Sep;14(9):815-8.

      Laminin receptor 1: a novel protein interacting with human circadian clock protein, hPer1. Neurol Res. 2007 Jul;29(5):429-34.

      Association of the 54-nucleotide repeat polymorphism of hPer3 with heroin dependence in Han Chinese population. Genes Brain Behav. 2008 Feb;7(1):26-30.

      The extracellular signal-regulated kinase signaling pathway is involved in the modulation of morphine-induced reward by mPer1. Neuroscience. 2007 Apr 25;146(1):265-71.

      Altered expression of circadian clock gene, mPer1, in mouse brain and kidney under morphine dependence and withdrawal. J Circadian Rhythms. 2006 Aug 22;4:9.

      Circadian gene mPer2 overexpression induces cancer cell apoptosis. Cancer Sci. 2006 Jul; 97(7): 589-96.

      RACK1, a novel hPER1-interacting protein. J Mol Neurosci. 2006;29(1):55-63.

      The role of mPer1 in morphine dependence in mice. Neuroscience. 2005;130(2):383-8.