李 浇

发布时间:2022-07-15      作者:学科办      审核:刘肖珩      编辑:吴靓      点击:
审核人 刘肖珩

李浇,副教授,硕士生导师

邮箱:joyleeql2019@163.com

【简历】

四川大学与美国俄亥俄州立大学联合培养博士。主持和主研多项国家自然科学基金,发表国际高质量论文10余篇。主要研究:1.胞内寄生病原体免疫逃逸机制;2.胞内寄生病原体毒力相关基因的筛选及功能鉴定;3.胞内寄生病原体基因编辑。

【主要承担项目】

1. 主持:

国家自然科学基金-青年项目:《CyPA在杜氏利什曼原虫胞内寄生过程中的生物学功能研究》,批准经费30万元;

2. 主研:

国家自然科学基金-面上项目:《西北干旱荒漠区利什曼原虫、白蛉和蜥蜴的协同进化研究》,批准经费69.6万,负责人:陈达丽。

【代表性论文】(*共同第一作者;#共同通讯作者):

1. Jinlei He, Fan Huang, Jianhui Zhang, Qiwei Chen, Zhiwan Zheng, Qi Zhou, Dali Chen,Jiao Li*, Jianping Chen*.Vaccine design based on 16 epitopes of SARS-CoV-2 spike protein.J Med Virol. 2021;93(4):2115 -2131. (IF: 20.693)

2. Zhiwan Zheng#,Jinlei He#,Tao Luo,Jianhui Zhang,Qi Zhou,Shuangshuang Yin,Dali Chen,Jie Luo,Jianping Chen*,Jiao Li*.Mutation Characteristics and Phylogenetic Analysis of FiveLeishmaniaClinical Isolates.Animals.2022, 12(3): 321.

3. Jianhui Zhang#,Jiao Li#, Kaifeng Hu#, Qi Zhou, Xiaoxiao Chen, Jinlei He,Shuangshuang Yin, Yangjian Chi, Xuechun Liao, Yuying Xiao, Hanxiao Qin,Zhiwan Zheng* and Jianping Chen*.Screening Novel Vaccine CandidatesforLeishmania DonovanibyCombining Differential Proteomicsand Immunoinform atics Analysis.2022.

4. Jianhui Zhang#,Jinlei He#,Xuechun Liao,Yuying Xiao,Chang Liang,Qi Zhou,Han Chen,Zhiwan Zheng,Hanxiao Qin,Dali Chen,Qiwei Chen,Jiao Li*,Jianping Chen*.Development of dominant epitope-based vaccines encoding Gp63, Kmp-11 and Amastin against visceral leishmaniasis,Immunobiology, 2021, 226(3): 152085.

5. Qi Zhou#,Jiao Li#, Xianguang Guo , Jinlong Liu , Qi Song , Xiong Gong , Han Chen, Jianhui Zhang, Jinlei He, Zhiwan Zheng, Dali Chen*, Jianping Chen*.Records of three mammal tick species parasitizing an atypical host, the multi-ocellated racerunner lizard, in arid regions of Xinjiang, China.Parasit Vectors. 2021;14(1):135.

6. Zhiwan Zheng, Jianping Chen, Guangxu Ma, Abhay R Satoskar,Jiao Li*. Integrative genomic, proteomic and phenotypic studies ofLeishmania donovanistrains revealed genetic features associated with virulence and antimony-resistance.Parasit Vectors. 2020;13(1):510.

7. ZhiWan Zheng#,Jiao Li#, Han Chen, Jin‑Lei He, Qi‑Wei Chen, Jian‑Hui Zhang, Qi Zhou, Da‑Li Chen*, Jian‑Ping Chen*. Evaluation of in vitro antileishmanial efficacy of cyclosporin A and its non-immunosupp ressive derivative, dihydrocyclosporin A.Parasit Vectors. 2020;13(1):94.

8. Han Chen#,Jiao Li#, Junrong Zhang, Xianguang Guo, Jinlong Liu, Jinlei He, Qi Song, Jianhui Zhang, Minli Chen, Zhiwan Zheng, Dali Chen*, Jianping Chen*. Multi-locus characterization and phylogenetic inference ofLeishmaniaspp. in snakes from Northwest China.PLoS One. 2019;14(4): e0210681.

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