邓东

发布时间:2020-12-18      作者:学科办      审核:刘肖珩      编辑:吴靓      点击:
审核人 刘肖珩

简历

2016年1月至今,四川大学教授、博士生导师

2014年1月-2016年1月,清华大学医学院博士后

2010年9月-2014年1月,清华大学生命科学学院博士

研究领域

1. 真核生物膜转运蛋白的结构生物学研究

2. 药物分子跨膜转运的分子机制研究

3. 肿瘤等疾病中物质跨膜转运机制研究

4. 囊泡神经递质转运的分子机制研究

近期论文

1.Deng, D.*, Sun, P.*, Yan, C., Ke, M., Jiang, X., Ren, W., Hirata, K., Yamamoto, M., Fan, S., & Yan, N. (2015). Molecular basis of ligand recognition and transport by glucose transporters.Nature. 526,391-396. (*, co-first author)

2.Deng, D.*, Xu, C.*, Sun, P.*, Wu, J.*, Yan, C., Hu, M., & Yan, N. (2014). Crystal structure of the human glucose transporter GLUT1.Nature. 510, 121-125. (*, co-first author)

3.Deng, D.*, Yan, C.*, Pan, X.*, Mahfouz, M., Wang, J., Zhu, J. K., Shi, Y., & Yan, N. (2012). Structural basis for sequence-specific recognition of DNA by TAL effectors.Science. 335, 720-723. (*, co-first author)

4.Deng, D., Yan, C., Wu, J., Pan, X., & Yan, N. (2014). Revisiting the TALE repeat.Protein & cell. 5, 297-306.

5.Yin, P.*,Deng, D.*, Yan, C., Pan, X., Xi, J. J., Yan, N., & Shi, Y. (2012). Specific DNA-RNA hybrid recognition by TAL effectors.Cell reports.2, 707-713. (*, co-first author)

6.Deng, D.*, Yin, P.*, Yan, C., Pan, X., Gong, X., Qi, S., Xie, T., Mahfouz, M. Zhu, J. K., Yan, N., & Shi, Y. (2012). Recognition of methylated DNA by TAL effectors.Cell research. 22, 1502-1504. (*, co-first author)

7.Deng, D.& Yan, N. (2016) GLUT, SGLT, and SWEET: Structural and mechanistic investigations of the glucose transporters.Protein Sci. 25, 546–58.

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