医学博士 副教授 UTSW Medical Center 内科 博士后 University of Minnesota 神经学 博士后 四川大学 法医病理学与法医临床学 博士 主讲课程: 法医学(留学生),医学汉语-法医学(留学生),法医病理学。 研究方向: 1. 法医病理学:主要基于转录及转录调控分析,探寻法医病理学中损伤/疾病的分子诊断靶点。 2. 神经科学:通过单细胞/Bulk转录组测序及生物信息学分析,结合基因敲入/敲除、光遗传等Gain/Loss of Function研究方法,解析创伤性脑损伤、爆炸性脑损伤的病理机制。 在研项目: 1. 国家自然科学基金项目(82202077),负责人 2. 四川省人社厅特别资助项目(2022LF20),负责人 3. 四川省科技厅项目(23NSFSC4762),负责人 4. 成都市第二批科技项目(2022-YF05-01564-SN),负责人 5. 司法部重点实验室开放课题(KF202202),负责人 Selective Publications: 1. Chen X*, Wyler SC*... Comparative transcriptomic analyses of developing melanocortin neurons reveal new regulators for the anorexigenic neuron identity. Journal of Neuroscience. 2020 Apr 15;40(16):3165-77. (Nature Index) 2. Xu Y...Chen X#, Liang W#. Scientific Evidences of Calorie Restriction and Intermittent Fasting for Neuroprotection in Traumatic Brain Injury Animal Models: A Review of the Literature. Nutrients. 2022 Mar 30;14(7):1431. (Correspondent, Q1, IF: 6.7) 3. Yuwen Sun...Xiameng Chen#, Weibo Liang#. Optogenetics for Understanding and Treating Brain Injury: Advances in the Field and Future Prospects. International Journal of Molecular Sciences. Int. J. Mol. Sci. 2022, 23(3), 1800. (Correspondent, Q1, IF: 6.02) 4. Ravinder Verma, Xiameng Chen...Q. Richard Lu. Olig1/2-expressing intermediate lineage progenitors are predisposed to PTEN/p53-loss-induced gliomagenesis and harbor specific therapeutic vulnerabilities. Cancer Research. 2023 (Nature Index, IF: 13.3) 5. Manrui Li*, Xiameng Chen*...Single-nucleus profiling of adult mice sub-ventricular zone after blast-related traumatic brain injury. SCI DATA. 2023 (Q1, IF: 8.5) 6. Shuqiang Cao...Xiameng Chen#, Weibo Liang#. Intermittent Fasting Enhances Hippocampal Npy Expression to Promote Neurogenesis Following Traumatic Brain Injury. Nutrition. 2022 Jan 30, 111621. (Correspondent, Q1, IF: 4.88) 7. Yang Q...Chen X#, Liang W#. Single-cell transcriptome study in forensic medicine: prospective applications. International Journal of Legal Medicine. 2022 Sep 9:1-7. (Correspondent, Q1) 8. Li L...Chen X...Sohn JW, Liu C. The atypical antipsychotic risperidone targets hypothalamic melanocortin 4 receptors to cause weight gain. Journal of Experimental Medicine. 2021 May 12;218(7):e20202484. (Nature Index, IF: 17) 9. Li L...Chen X...Liu C. Delineating a serotonin 1B receptor circuit for appetite suppression in mice. Journal of Experimental Medicine. 2022 Jul 7;219(8):e20212307. (Nature Index, IF: 17) |