Ashley Bush, academician of the University of Melbourne of Australia, gave a wonderful academic seminar in Lecture Hall of the 5thteaching building on October 24, 2017 at 10:00-11:30 am. Dr. Bush was invited by Prof. Peng Lei, associate dean of the college. Our department heads, teachers and students of our college attended the lecture, the report was chaired by Prof. Changlong Li, the party chief of secretary the college.
Prof. Li Chairing the Lecture
Prof. Ashley Bush made an academic lecture titled “Targeting Iron and Ferroptosis in Alzheimer’s Disease”. Prof. Ashley Bush shared the history of the past 30 years of their careers involvement of abnormal metal ions including zinc, iron in the pathogenesis of neurodegenerative diseases and regulation of amyloid beta, tau and other proteins. Prof. Ashley Bush combined clinical symptoms with basic research to explain the relationship between the content of iron in the brain of AD patients may be related to the reduction of β-amyloid precursor protein (APP).
Prof. Ashley Bush on the Lecture
Prof. Ashley Bush also shared a new discovery about Aducanumab antibody can reduce deposition of β-amyloid protein in AD patients, and regulated the level of iron in neuron through the drug was proposed to treat Alzheimer’s Disease based on the role of iron in neuronal activity.
Lecture Scene
After the lecture, students and teachers enthusiastically asked questions, Prof. Ashley Bush interacted positively with them, sharing academic viewpoints, and on-site atmosphere was extremely active.
The lecture aroused the great interest of the students and teachers, and also provided new ideas and methods for the research and exploration while broadening our academic horizons.
CV of Professor Ashley Bush:
Ashley Bush (MBBS, DPM, FRANZCP, PhD, FTSE, FAHMS, FAPA) is Professor of Neuroscience at the University of Melbourne; Director of the Oxidation Biology Unit at the Florey Institute of Neuroscience & Mental Health; Co-Director of Biomarker Development for the Australian Imaging, Biomarkers and Lifestyle Study of Aging; and Chief Scientific Officer for the Cooperative Research Centre for Mental Health. As a neuroscientist and ageing researcher, Prof Bush has made valuable contributions over the past 25 years to our understanding of the importance of metal biology and oxidative stress in the function and dysfunction of the brain, especially as it is ages and becomes predisposed to degeneration. He has accrued 360+ publications and 26 patents, has presented over 280 invited lectures worldwide (including 24 Plenary), is currently the most highly cited neuroscientist in Australia and is rated in the top 1% of neuroscience researchers worldwide for high impact citations. The steady increase in the proportion of world publications relating to metals in the brain can be largely attributed to the impact of Prof Bush’s work and his pioneering Metals Theory of Age-related Neurodegeneration. Over the course of his career, he has received several awards and honours for his research, most recently the NHMRC Australia Fellowship (2011); Victoria Prize for Science and Innovation (2014); Woodward Medal in Science and Technology (2014); NHMRC Senior Principal Research Fellowship (2016), and citation in The World's Most Influential Scientific Minds (Thomson Reuters, 2014, 2015).
https://www.florey.edu.au/users/ashleyib