Dr.Yunqing LI,Professor
Tel:029-84772706
e-mail: yunqing@fmmu.edu.cn
Education background:
1. 1979.09-1984.07 B.MS.,The Fourth Military Medical University, PR China
2. 1984.09-1987.02 M.MS., The Fourth Military Medical University, PR China
3. 1987.03-1990.07 Ph.D., The Fourth Military Medical University, PR China
4. 1991.10-1993.04 Ph.D., Faculty of Medicine, Kyoto University, Japan
Career Highlight:
1. Lecturer, Department of Anatomy, Histology and Embryology, The Fourth Military Medical University, PR China (1990-1992)
2. Associate Professor, Department of Anatomy, Histology and Embryology, The Fourth Military Medical University, PR China (1993-1994)
3. Professor, Department of Anatomy, Histology and Embryology, The Fourth Military Medical University, PR China (1995-1996)
4. Professor and Director, Department of Anatomy, Histology and Embryology, The Fourth Military Medical University, PR China (1997-present)
Research Interest:
1. Neural mechanisms underlying nociception and analgesia, especially on the central endogenous pain control system
2. Mechanisms underlying the peripheral noxious information transmission
3. Regulatory mechanisms of the oro-facial movement and enteric movement
4. Visceral noxious information transmission pathway and regulatory mechanism
Awards:
1. 1996.01 National Natural Science Foundation of China for Distinguished Young Scholars
2. 1998.08 Qiushi Award of the China Association for Science and Technology
3. 2002.01 Distinguished Visiting Professor of the Chang Jiang Scholars Program of China
4. 2003.07 The first prize of Provincial Science and Technology Awards in Shaanxi Province
5. 2005.07 The first prize of Provincial Science and Technology Awards in Shaanxi Province
6. 2017.07 The first prize of Provincial Science and Technology Awards in Shaanxi Province
7 2017.07 Anatomist Excellence Award of the International Committee of Symposia on Morphological Sciences
8. 2009.10 The first prize of National Science and Technology Awards in China
9. 2017.10 Recipient of Science and Technology Progress Prize from the Ho Leung Ho Lee Foundation in China
1. Zhao ZQ, Liu XY, Jeffry J, Karunarathne WKA, Li JL, Munanairi A, Zhang XY, Li H, Sun YG, Wan L, Wu ZY, Kim S, Huo FQ, Mo P, Barry DM, Zhang CK, Kim JY, Gautam N, Renner KJ,Li YQ, Chen ZF. Descending Control of Itch Transmission by the Serotonergic System via 5-HT1A-Facilitated GRP-GRPR Signaling.Neuron, 2015, Article Number: 12347,http://dx.doi.org/10.1016/j.neuron. 2014.10.003
2. Chen T, Lu JS, Song Q, Liu MG, Koga K, Descalzi D,Li YQ*, Zhuo M*. Pharmacological rescue of cortical synaptic and network potentiation in a mouse model for fragile X syndrome.Neuropsychopharmacology, 2014, 39(8): 1955-1967.
3. Qi J, Lu YC, ZhangT, Wang W, Dong YL,Li YQ*. Activation of extracellular signal-regulated kinase1/2 in the medial prefrontal cortex contributes to stress-induced hyperalgesia.Molecular Neurobiology, 2014,50(3): 1013-1023.
4. Wu SX, Wang W, Li H, Wang YY, Feng YP,Li YQ*.The synaptic connectivity that underlies the noxious transmission and modulation within the superficial dorsal horn of the spinal cord.Prog Neurobiol. 2010, 91(1): 38-54.
5. Mei XP, Zhang H, Wang W, Wei YY, Zhai MZ, Wang W, Xu LX,Li YQ*.Inhibition of spinal astrocytic c-Jun N-terminal kinase (JNK) activation correlates with the analgesic effects of ketamine in neuropathic pain.J Neuroinflammation. 2011, 8(1):6-18.
6. Chen T, Taniguchi W, Chen QY, Tozaki-Saitoh H, Song Q, Liu RH, Koga K, Matsuda T, Sugimura Y, Wang J, Li ZH, Lu YC, Inoue K, Tsuda M,Li YQ*,Nakatsuka T*,Zhuo M*. Top-down descending facilitation of spinal sensory excitatory transmission from the anterior cingulate cortex.Nature Communications, 2018 May 14; 9(1):1886.
7. Zhang FX, Ge SN, Dong YL, Shi J, Feng YP, Li Y,Li YQ*,Li JL*. Vesicular glutamate transporter isoforms: the essential players in the somatosensory systems.Progress in Neurobiology, 2018; 171(2018): 72-89.
8.Wan FP, Bai Y, Kou ZZ, Zhang T, Li H, Wang YY,Li YQ*. Endomorphin-2inhibition of substance P signaling within lamina I of the spinal cord is impaired in diabetic neuropathic pain rats.Frontiers in Molecular Neuroscience, 2017 Jan 10;9:167
9.Qi J, Li H, Zhao TB, Lu YC, Zhang T, Li JL, Dong YL,Li YQ*. Inhibitory effect of endomorphin-2 binding to the µ-opioid receptor in the rat pre-Bötzinger complex on the breathing activity.Molecular Neurobiology, 2017 Jan;54(1):461-469
10.Kou ZZ, Wan FP, Bai Y, Li CY, Hu JC, Zhang GT, Zhang T, Chen T, Wang YY, Li H,Li YQ*. Decreased endomorphin-2 andμ-opioid receptor in the spinal cord are associated with painful diabetic neuropathy.Frontiers in Molecular Neuroscience, 2016; 9: 80
11.Chen T, Li J, Feng B, Hui R, Dong YL, Huo FQ, Zhang T, Yin JB, Du YQ,Li YQ*. Mechanism underlying the analgesic effect exerted by endomorphin-1 in the rat ventrolateral periaqueductal gray.Molecular Neurobiology, 2016; 53(3): 2036–2053
12. Zhao ZQ, Wan L, Liu XY, Huo FQ, Li H, Barry DM, Krieger S, Kim S, Liu ZC, Xu J, Rogers BE,Li YQ, Chen ZF.Cross-inhibition of NMBR and GRPR signaling maintains normal histaminergic itch transmission.Journal of Neuroscience, 2014; 34(37):12402~12414
13. Qi J, Chen C, Lu YC, Zhang T, Xu H, Cui YY, Chen YZ, Wang W, Dong YL,Li YQ*.Activation of extracellular signal-regulated kinase1/2 in the medial prefrontal cortex contributes to stress-induced hyperalgesia.Molecular Neurobiology, 2014; 50(3):1013~1023
14.Chen L, Zhu L, Wang K, Wang W, Mei XP, Liu T, Zhang FX, Wang W, Chen T,Li YQ*.Antinociceptive effect of prostatic acid phosphatase in a rat model of cancer-induced bone pain.Pain Physician, 2013; 16(6):533~546
15.Kou ZZ,Li CY, Tang J, Hu JC,Qu J, Liao YH, Wu SX, Li H,Li YQ*. Down-regulation of insulin signaling is involved in painful diabetic neuropathy in type 2 diabetes.Pain Physician, 2013; 16(2):E71~E83