Title: Professor, PhD supervisor

Professor Zhou graduated from West China Medical University with a bachelor's degree in 1985. She received a master's degree in medicine from West China Medical University in 1994 and a PhD in medicine from Sichuan University in 2003.

Member of the Chinese Society of Anatomy, member of the Sichuan Society of Anatomy, editorial board member of the Journal of Jiangsu University (Medical Edition), and peer review expert of the National Natural Science Foundation of China.

Research areas:

Professor Zhou's main research direction is regeneration and repair after mammalian central nervous system injury. Her research found that after partial dorsal root injury, the spinal dorsal horn and intact dorsal root ganglion can synthesize some neurotrophic factors to promote intact dorsal root sprouting on the medial branch of the spinal cord. Acupuncture can strengthen this process. In recent years, she has been involved in the study of the mechanism of nerve damage in diabetes. The experimental results suggest that the neuronal apoptosis of some brain stem nuclei caused by chronic restraint stress may be an important cause of insulin-resistant hyperglycemia. The above research results provide a theoretical basis for the mechanism of central nervous system plasticity and the mechanism of acupuncture; it also opens up new ideas for the study of the pathogenesis of diabetes.

Academic achievements:

So far, Professor Zhou has published 30 academic papers in Chinese academic journals. Published more than 10 academic papers in international academic journals, among which the more influential professional magazines Apoptosis, Neuropeptides, Autonomic Neuroscience: Basic and Clinical, Cell Transplantation. As the project leader,she presided over 2 National Natural Science Funds, 1 Provincial Science and Technology Commission Fund, and 1 School-level Youth Fund. As the main researcher, he participated in the research work of nearly 10 topics at all levels. Editor-in-chief and 15 textbooks. Won the "First Prize for Excellent Teaching" of Sichuan University, the "Excellent Young Teacher" Award for the "One Professional and Multi-ability" Talented Activity of 100,000 Middle School Students in Chengdu, the "Top Ten Teacher Ethics Award" of Sichuan University, and the "Excellent Class Teaching Quality" Award "and" Tang Lixin Teaching Master "awards.

Research funds hosted:

1. Project of National Natural Science Foundation of China: the role of α-SN and miR-138 in the plasticity of cerebral motor cortex in rats with spinal cord transection and the regulation of α-SN by miR-138 (Grant No. 81171176)

2. Project of National Natural Science Foundation of China: Acupuncture promotes the spatiotemporal changes of NTFs and mRNA during the repair of spinal cord injury (Grant No. 39800191)

3. Basic Research Fund Project of Sichuan Science and Technology Department: Study on the mechanism of acupuncture to promote the collateral spinal cord afferent collateral budding-separation and purification

Representative paper:

1. You-Cui Wang,Guo-Ying Feng,Qing-Jie Xia,Yue Hu, Yang Xu,Liu-Lin Xiong, Zhi-Wei Chen, Hang-Ping Wang,Ting-Hua Wang, Xue Zhou. Knockdown of α-synuclein in cerebral cortex promotes neuronal behavior repairassociated with apoptotic inhibition and neurotrophic expression in spinal cord transected rats.Apoptosis.Published on line:28,January,2016.DOI: 10.1007/s10495-016-1218-5

2. Yonghua Zong, Ling Jiang, Mingxiao Zhang, Fangfang Zhou, Wenqian Qi, Shuai Li, Huijun Yang, Yu Zou, Qingjie Xia,Xue Zhou,Xiaosong Hu and Tinghua Wang.Limb remote ischemic postconditioningprotects cerebral ischemia from injury associated with expression of HIF?1α in rats.BMC Neurosci (2015) 16:97

3. Xin Li, Ying Feng,, Wei Wu, Jia Zhao, Chunmei Fu, Yang Li, Yangnan Ding, Binghuo Wu, Yanju Gong, Guizhi Yang and Xue Zhou. Sex differences between APPswePS1dE9 mice in A-beta accumulation and pancreatic islet function during the development of Alzheimer’s disease.Laboratory Animals Lab Anim. 2015 Oct 30. pii: 0023677215615269. [Epub ahead of print]

4. Liu SJ, Zou Y, Belegu V, Lv LY,Lin N, Wang TY, MecDonald JW, Zhou X, Xia QJ, Wang TH. Co-grafting of neural stem cells with olfactory ensheathing cells promotes neuronal restoration in traumatic brain injury with an anti-inflammatory mechanism.J Neuroinflammation. 2014;11(1):66

5. Fu XM, Liu SJ, Dan QQ, Wang YP, Lin N, Lv LY, Zou Y, Liu S, Zhou X, Wang TH. Combined bone mesenchymal stem cells and olfactory ensheathing cells transplantation promote neural repair associated with CNTF expression in traumatic brain injured rats.Cell Transplant. 2014 Mar 7.[Epub ahead of print]PMID:24612678

6. Xiao-Jing Li, Wei Zhang, Bing Liang , Xiang Zheng, Xue Zhou. Up-expression of GAD65 in the amygdala of the rat model of chronic immobilization stress with elevated blood glucose. Autonomic Neuroscience:Basic and Clinical, 2012;166: 77–80

7. Xiang Zheng, Xue Zhou. Neuron impairment or loss in brain may be responsible for type 2 diabetes and essential hypertension. Nature Preceding. 10101/npre.2010.4187.1

8. Xue Zhou, Jin-Wei Yang, Wei Zhang, Ke-Qun Ou, Hao-Li Zhou, Yu-Qiong Ma, Si-Xiu Chen, Li-Yan Li, Ting-Hua Wang. Role of NGF in spared DRG following partial dorsal rhizotomy in cats.Neuropeptides. 2009; 43: 363–369

Contact: 028-85501384, zhouxue7239@163.com,

Mailing address: No. 17, Section 3, Renmin South Road, Chengdu, Sichuan Province, West China School of Basic Medicine and Forensic Medicine, Sichuan University

Department of Histology and Embryology and Neurobiology, 610041