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Yu ZHENG

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Yu ZHENG,Ph.D

Professor

Department of Physiology

West China School of Basic Medical Sciences & Forensic Medicine

Sichuan University

Address:

No.17 the 3rd section of South People Road, Chengdu, Sichuan Province

Phone Number:86-28-85502389

Email Address: yzheng@scu.edu.cn

Graduated from Sichuan Medical College in 1977, obtained master degree from West China University of Medical Sciences in 1985 and doctoral degree from Universite Aix-Marseille III, France in 1990.

Professor of Physiology (1997- ), head of Department of Physiology (1994-2001), and vice dean of West China School of Basic Medical Sciences and Forensic Medicine (2001-2011)in Sichuan University,executive member of the council of Chinese Association of Physiological Sciences (1998-2010),chairman of Physiological Society of Sichuan Province (2006-2015), member of editorial board of ActaPhysiologicaSinica, Journal of Biomedical Engineering, Journal of Sichuan University (Medical Science Edition) and some others.

The major research interest has been focused on neurobiology, especially the neural control of breathing and respiration-related activities. The main works we previously did include the effects of stimulatingacupoint“Renzhong” on respiration and the underlying mechanism in rabbits, the electrophysiological and morphological properties of the respiratory neurons in medulla oblongata in rats, the roles of the medullary respiratory neurons in regulation of respiration and respiration-related activities in cats, and the effects of ischemia or hypoxia of brainstem on respirationand the protective strategies in rats. The recent main work focuses onthe biological actions of H2S in rats.

RECENT MAIN PUBLICATIONS (AS CORRESPONDING AUTHOR):

1. Fusheng Zhao, Fang Lei, Senfeng Zhang, Xiang Yan, Wen Wang, Yu Zheng. Hydrogen sulfide alleviates placental injury induced by maternalcigarette smoke exposure during pregnancy in rats.Nitric Oxide (2017) 1-10.doi: 10.1016/j.niox.2017.07.003. [Epub ahead of print]

2. Senfeng Zhang, Fang Lei, Fusheng Zhao, Xiang Yan, Wen Wang, Yu Zheng. Hydrogen sulfide ameliorates prenatal cigarette smoke exposure-inducedimpairment of respiratory responses to hypercapnia in neonatal rats.Respiratory Physiology & Neurobiology 243:1-6, 2017.

3. Yan Ding, XuefeiHou, Li Chen, Hua Zhou, Yanju Gong, Liqun Dai, Yu Zheng. Heme oxygenase-1 dependant pathway contributes to protection by tetramethylpyrazine against chronic hypoxic injury on medulla oblongata in rats.Journal of Neurological Sciences 361:101-111, 2016.

4. Hui Li,Li Chen,Xuefei Hou,Hua Zhou,Yu Zheng.Hydrogen sulfideattenuates hypoxia-induced respiratory suppressionin anesthetized adult rats.Respiratory Physiology & Neurobiology 220:1-9, 2016.

5. Fang Lei, Xiang Yan, Fusheng Zhao, Senfeng Zhang, Qilan Zhang, Hua Zhou, Yu Zheng. Impairment of central chemoreception in neonatal rats induced by maternal cigarette smoke exposure during pregnancy.PLoS ONE 10:e0137362, 2015.doi:10.1371/journal.pone.0137362.

6. Hui Li, XuefeiHou, Yan Ding, LihongNie, Hua Zhou, Zheng Nie, Yuhong Tang, Li Chen and Yu Zheng. Effects of H2S on the central regulation of respiration in adult rats.NeuroReport 25:358-366, 2014.

7. Li Chen, Jie Zhang, Yan Ding, Hui Li, LihongNie, Hua Zhou, Yuhong Tang, Yu Zheng. Site-specific hydrogen sulfide-mediated central regulation of respiratory rhythm in medullary slices of neonatal rats.Neuroscience 233:118-126, 2013.

8. LihongNie, Yajie Hu, Xiang Yan, Mingqiang Li, Li Chen, Hui Li, Xianke Li, Hua Zhou, Yu Zheng. The anti-apoptotic effect of hydrogen sulfide attenuates injuries to the medullary respiratory centers of neonatal rats subjected to in utero cigarette smoke exposure.Respiratory Physiology & Neurobiology 188:29-38, 2013.

9. Li Chen, Jie Zhang, Yan Ding, Hui Li, LihongNie, Xiang Yan, Hua Zhou. Yu Zheng. KATPchannels of parafacial respiratory group (pFRG) neurons are involved in H2S-mediated central inhibition of respiratory rhythm in medullary slices of neonatal rats.Brain Research 1527:141-148, 2013.

10. Mingqiang Li, LihongNie, Yajie Hu, Xiang Yan, LianXue, Li Chen, Hua Zhou, Yu Zheng. Chronic intermittent hypoxia promotes expression of 3-mercaptopyruvate sulfurtransferase in adult rat medulla oblongata.Autonomic Neuroscience 179:84-89, 2013.

11. Yan Ding, XuefeiHou, Li Chen, Hui Li, Yuhong Tang, Hua Zhou, Shu Zhao, Yu Zheng. Protective action of tetramethylpyrazine on medulla oblongata in rats with chronic hypoxia.Autonomic Neuroscience 173:45-52, 2013.

TEXTBOOK EDITOR-IN-CHIEF:

“Direction of Learning and Problem Sets of Respiratory System”, The People’s Medical Publishing House, 2016.

“Textbook of Respiratory System”, The People’s Medical Publishing House, 2015.

“Textbook of Physiology”, TheHigher Education Press, 2010.

“Textbook of Physiology”, TheSichuan University Press, 2005.

TEXTBOOK ASSOCIATE EDITOR-IN-CHIEF:

“Textbook of Physiology”, (8 Year Educational System), 3rd Ed, The People’s Medical Publishing House, 2015.

“Digital Textbook of Physiology”, The People’s Medical Publishing House, 2015.

TEXTBOOK EDITOR:

“Textbook of Physiology”, 8th Ed, The People’s Medical Publishing House, 2013.

“Textbook of Physiology”, (8 Year Educational System), 2nd Ed, The People’s Medical Publishing House, 2010.

“Textbook of Physiology”, 7th Ed, The People’s Medical Publishing House, 2008.

“Textbook of Physiology”, (8 Year Educational System), 1st Ed, The People’s Medical Publishing House, 2005.

“Textbook of Physiology”, 6th Ed, The People’s Medical Publishing House, 2003.

“Textbook of Physiology”, 5th Ed, The People’s Medical Publishing House, 2000.

“Textbook of Physiology”, 4th Ed, The People’s Medical Publishing House, 1996.

BOOK CHAPTER EDITOR:

“Medical Encyclopedia of China: Sub-volume of Human Physiology”, China union medical university press, 2017.

“Human Physiology”, 4th Ed, The People’s Medical Publishing House, 2015.