【科研领域】
免疫调节与肿瘤、免疫调节参与毒品成瘾、致精神障碍的机制
【主要成果】
1. 已获国家授权发明专利4项
2. 已发表论文60多篇,近年发表代表性文章如下(*通讯作者,#共同通讯作者):
Wang P, Hu J, Min S, Chen C, Zhu Y, Pan Y, Wei D, Wang X*. Recombinant Phaseolus vulgaris phytohemagglutinin L-form expressed in the Bacillus brevis exerts in vitro and in vivo anti-tumor activity through potentiation of apoptosis and immunomodulation. Int Immunopharmacol. 2023 Jun 1;120:110322.
Wang P, Hu J, Duan J, Min S, Chen C, Zhu Y, Pan Y, Wang Y, Wei D, Wang X*. Preparation of a novel monoclonal antibody against active components of PHA-L from Phaseolus vulgaris and its functional characteristics. BMC Biotechnol. 2022 Oct 29;22(1):32.
Wang P, Leng X, Duan J, Zhu Y, Wang J, Yan Z, Min S, Wei D, Wang X*. Functional Component Isolated from Phaseolus vulgaris Lectin Exerts In Vitro and In Vivo Anti-Tumor Activity Through Potentiation of Apoptosis and Immunomodulation. Molecules. 2021 Jan 18;26(2):498.
Wang Q, Wang PP, Zhang L, Tessema L, Bai L, Xu XL, Li Q, Zheng XL, Saxton B, Chen WS, Willink R, Li ZP, Zhang L, Belinsky SA, Wang X#, Zhou B#, Lin Y#. Epigenetic Regulation of RIP3 Suppresses Necroptosis and Increases Resistance to Chemotherapy in Non-Small Cell Lung Cancer. Transl Oncol. 2020 Feb;13(2):372-382.