科研项目：

B7-H3在调控人乳腺癌细胞糖代谢中的作用及机制（81201559），国家自然科学基金青年基金项目，2013.1-2015.12，已结题，负责人

B7-H3在调控人结直肠癌细胞糖代谢中的作用及机制 (J11(2)201204)，国家基础科学人才培养基金能力提高项目子项目（J1103604），2012.12-2014.12，已结题，负责人

糖酵解在乳腺癌侵袭转移中的作用和干预研究（81272907），国家自然科学基金面上项目，2013.1-2016.12，已结题，第一主研

文章：

1. Lim S*, Liu H*#, Madeira da Silva L, Arora R, Liu Z, Phillips JB, Schmitt DC, Vu T, McClellan S, Lin Y, Lin W, Piazza GA, Fodstad O#, Tan M#. Immunoregulatory Protein B7-H3 Reprograms Glucose Metabolism in Cancer Cells by ROS-Mediated Stabilization of HIF1a. Cancer Res. 2016;76(8);2231-42. (*co-first authors, #co-corresponding authors)

2. Liu Z, Liu H, Desai S, Schmitt DC, Zhou M, Khong HT, Klos KS, McClellan S, Fodstad O, Tan M. miR-125b functions as a key mediator for snail-induced stem cell propagation and chemoresistance. J Biol Chem. 2013 Feb 8;288(6):4334-45.

3. Ding Y, Liu Z, Desai S, Zhao Y, Liu H, Pannell LK, Yi H, Wright ER, Owen LB, Dean-Colomb W, Fodstad O, Lu J, LeDoux SP, Wilson GL, Tan M. Receptor tyrosine kinase ErbB2 translocates into mitochondria and regulates cellular metabolism. Nat Commun. 2012, 3: 1271.

4. Zhao Y, Liu H, Liu Z, Ding Y, LeDoux SP, Wilson GL, Voellmy R, Lin Y, Lin W, Nahta R, Liu B, Fodstad O, Chen J, Wu Y, Price JE, and Tan M. Overcoming trastuzumab resistance in breast cancer by targeting dysregulated glucose metabolism. Cancer Res. 2011, 71(13); 4585-97.

5. Liu H, Tekle C, Chen YW, Kristian A , Zhao YH, Zhou M, Liu ZX, Ding Y, Wang B, M?landsmo GM, Fodstad O, Tan M. B7-H3 silencing increases paclitaxel sensitivity by abrogating Jak2/Stat3 phosphorylation. Mol Cancer Ther. 2011, 10(6):960-71.

6. Zhao Y*, Liu H*, Riker AI, Fodstad O, Ledoux SP, Wilson GL, Tan M. Emerging metabolic targets in cancer therapy. Front Biosci. 2011, 16:1844-1860. ( *co-first authors)

7. Zhao YH, Zhou M, Liu H, Ding Y, Khong HT, Yu D, Fodstad O, Tan M. Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth. Oncogene. 2009, 28(42): 3689-3701.

8. Zhou M, Zhao Y, Ding Y, Liu H, Liu Z, Fodstad O, Riker AI, Kamarajugadda S, Lu J, Owen LB, Ledoux SP, Tan M. Inhibition of lactate dehydrogenase-A re-sensitizes Taxol-resistant cancer cells to Taxol. Mol Cancer. 2010, 9(1):33.

9. Zhou M, Liu Z, Zhao Y, Ding Y, Liu H, Xi Y, Xiong W, Li G, Lu J, Fodstad O, Riker AI, Tan M. MicroRNA-125b confers the resistance of breast cancer cells to paclitaxel through suppression of pro-apoptotic BCL-2 antagonist killer 1 (BAK1) expression. J Biol Chem. 2010, 285(28):21496-21507.