袁东智，男，1985年12月出生，现任四川大学华西基础医学与法医学院生理学副教授，硕士研究生导师，兼任四川省医学会医学教育专委会青年委员，四川生理科学会青年委员。主要研究方向生殖生理学、生殖内分泌学及生殖医学，近五年以来的工作集中在女性不孕症和男性无精症的病理机制研究。曾获四川省五一劳动奖章、全国五一劳动奖章。

主讲本科课程《生理学》、《机能实验学》，研究生课程《生殖生理学》。

教学获奖：

1. 第五届全国高校青年教师教学竞赛，医科组，一等奖第一名；

2. 四川省教学成果一等奖《以红色文化和卓越学术引领的基础医学拔尖创新人才培养体系的构建与实践》，排序第8；

3. 第五届四川省高校青年教师教学竞赛，医科组，第一名；

4. 四川大学教学成果二等奖《线上线下混合式生理学课程模式改革与实践》，负责人；

5. 四川大学“未来教学名师奖”；

6. 第三届中国生理学会全国高校人体生理学微课教学比赛二等奖；

7. 两届全国高等学校创新性机能实验设计大赛二等奖。

参编教材：

1. “十三五”医学英文规划教材《Human Physiology》，闫剑群主编，2020年，人民卫生出版社，负责内分泌章节编写；

2. “十四五”规划教材《人体解剖生理学（第8版）》，周华、杨向群主编，2022年，人民卫生出版社，负责生殖章节编写。

1. Min Liu, Yicheng Wang, Yongdan Ma, Xueqin Zhang, Lixue Zhang, Li Nie, Wenjing Guo, Dan Zhao, Jinhu Zhang, Dongzhi Yuan, Limin Yue. Activation of SGLT3a in endometrial epithelial cells induces paracrine stromal cell decidualization. J Cell Physiol. 2022 Feb;237(2):1532-1546.

2. Nie L, Zhang LX, Wang YC, Long Y, Ma YD, Liao LC, Dai XH, Cui ZH, Liu H, Wang ZQ, Ma ZY, Yuan DZ, Yue LM. Consistency and synchronization of AMPK-glycogen in endometrial epithelial cells are critical to the embryo implantation. Reproduction. 2022 Mar 30;163(5):293-307. doi: 10.1530/REP-21-0382. PMID: 35275843.

3. Wen-Jing Guo, Yi-Cheng Wang, Yong-Dan Ma, Zhi-Hui Cui, Li-Xue Zhang, Li Nie, Xue-Qin Zhang, Mei-Jiao Wang, Jin-Hu Zhang, Dong-Zhi Yuan, Li-Min Yue. Contribution of high-fat diet-induced PCSK9 upregulation to a mouse model of PCOS is mediated partly by SREBP2. Reproduction. 2021 Oct 28;162(6):397-410.

4. Li Nie, You-Bo Zhao, Dan Zhao, Yun Long, Yi Lei, Min Liu, Yi-Cheng Wang, Xue-Qin Zhang, Jin-Hu Zhang, Dong-Zhi Yuan, Li-Min Yue. Progesterone-induced miR-152 interferes with embryonic implantation by downregulating GLUT3 in endometrial epithelium. Am J Physiol Endocrinol Metab. 2019 Apr 1;316(4):E557-E567.

5. Meijiao Wang, Dan Zhao, Liangzhi Xu, Wenjing Guo, Li Nie, Yi Lei, Yun Long, Min Liu, Yichen Wang, Xueqin Zhang, Li Zhang, Hanna Li, Jinhu Zhang, Dongzhi Yuan, Limin Yue. Role of PCSK9 in lipid metabolic disorders and ovarian dysfunction in polycystic ovary syndrome. Metabolism. 2019 May;94:47-58.

6. Dong-Zhi Yuan, Yi Lei, Dan Zhao, Jun-Li Pan, You-Bo Zhao, Li Nie, Min Liu, Yun Long, Jin-Hu Zhang, Li-Min Yue. Progesterone-Induced miR-145/miR-143 Inhibits the Proliferation of Endometrial Epithelial Cells. Reprod Sci. 2019 Feb;26(2):233-243.

7. Hu Y, Wen S, Yuan D, Peng L, Zeng R, Yang Z, Liu Q, Xu L, Kang D. The association between the environmental endocrine disruptor bisphenol A and polycystic ovary syndrome: a systematic review and meta-analysis. Gynecol Endocrinol. 2018 May;34(5):370-377. doi: 10.1080/09513590.2017.1405931. Epub 2017 Nov 30. PMID: 29191127.

8. Hu Y, Yuan DZ, Wu Y, Yu LL, Xu LZ, Yue LM, Liu L, Xu WM, Qiao XY, Zeng RJ, Yang ZL, Yin WY, Ma YX, Nie Y. Bisphenol A Initiates Excessive Premature Activation of Primordial Follicles in Mouse Ovaries via the PTEN Signaling Pathway. Reprod Sci. 2018 Apr;25(4):609-620. doi: 10.1177/1933719117734700. Epub 2017 Oct 5. PMID: 28982275.

9. Li Nie, You-Bo Zhao, Jun-Li Pan, Yi Lei, Min Liu, Yun Long, Jin-Hu Zhang, Ying Hu, Ming-Qian Xu, Dong-Zhi Yuan, Li-Min Yue. Progesterone-Induced miR-152 Inhibits the Proliferation of Endometrial Epithelial Cells by Downregulating WNT-1. Reprod Sci. 2017 Oct;24(10):1444-1453.

10. J-L Pan, D-Z Yuan, Y-B Zhao, L Nie, Y Lei, M Liu, Y Long, J-H Zhang, L J Blok, C W Burger, L-M Yue. Progesterone-induced miR-133a inhibits the proliferation of endometrial epithelial cells. Acta Physiol (Oxf). 2017 Mar;219(3):683-692.